You can either take a taxi (about 60,10 Euros = 50 USD), or a bus.

Bus services are as follows:

 TFS to Puerto de la Cruz direct service (line 340). Departure times: 09:45, 14:00, 20:00 and 23:30h. Prices of one way ticket is about 7,20 Euros.

TFS to Puerto de la Cruz via Santa Cruz de Tenerife you must take 2 buses as follow:

 TFS to Santa Cruz de Tenerife bus terminal (line 341). Departure time: 06:50, 07:50, 08:50, 09:30, 10:30, 12:10, 13:10, 14:10, 14:50, 15:50, 16:50, 17:30, 18:30, 19:30, 20:10, 21:10, 22:10, 22:50 adn 01:30h. Price of one way ticket is about 4,60 Euros. Then take the following bus:

 Santa Cruz de Tenerife bus terminal to Puerto de la Cruz (line 102). Departure times: every 30 minutes until 20:30h. Additionally 21:15, 22:30 and 14:00h. Price of one way tickets is about 3,20 Euros.

The journey by bus takes about 1 1/2 - 2 hours depending on connections.

NOTE: There is a (steep uphill) walk from the bus terminal in Puerto de la Cruz to the Hotels. For this reason we recommend a taxi which will cost about 4,80 Euros.